Zanaflex is safe and effective for the treatment of a variety of patients who suffer from the debilitating symptoms of spasticity.
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ALS does not affect a person?s mental abilities or senses. ALS patients who have difficulty speaking may benefit from working with a speech therapist. Supportive therapies play a crucial role in the care of patients with ALS. Physical therapy, rehabilitation, use of braces or a wheelchair, or other orthopedic measures may be needed to maximize muscle function and general health. Choking is common. Patients may need a tube placed into their stomach for feeding (gastrostomy). Medications also may be prescribed to relieve pain (if any), depression, anxiety, sleep problems, and constipation. Medications such as baclofen (Lioresal) and tizanidine (Zanaflex) may be used to relieve severe spasticity. Physical therapy and special equipment can enhance patients' independence and safety throughout the course of ALS. Gentle, low-impact aerobic exercise such as walking, swimming, and stationary bicycling can strengthen unaffected muscles, improve cardiovascular health, and help patients fight fatigue and depression. Regular exercise and a physical therapy program can strengthen muscles and reduce spasticity. This helps maintain movements for as long as possible.
Multiple sclerosis is an autoimmune disease and affects the central nervous system. Central nervous system is made up of nerves that act as the body's messenger system. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body. Multiple sclerosis (MS) usually affects woman more than men. The disorder most commonly begins between ages 20 and 40, but can strike at any age. Multiple sclerosis affects neurons, the cells of the brain and spinal cord that carry information, create thought and perception, and allow the brain to control the body. Surrounding and protecting some of these neurons is a fatty layer known as the myelin sheath, which helps neurons carry electrical signals. MS causes gradual destruction of myelin (demyelination) and transection of neuron axons in patches throughout the brain and spinal cord. The name multiple sclerosis refers to the multiple scars (or scleroses) on the myelin sheaths. This scarring causes symptoms which vary widely depending upon which signals are interrupted. Multiple sclerosis may take several different forms, with new symptoms occurring either in discrete attacks or slowly accruing over time. Between attacks, symptoms may resolve completely, but permanent neurologic problems often persist, especially as the disease advances. MS currently does not have a cure, though several treatments are available that may slow the appearance of new symptoms. MS is believed to result from damage to the myelin sheath, the protective material which surrounds nerve cells. It is a progressive disease, meaning the damage gets worse over time. Inflammation destroys the myelin, leaving multiple areas of scar tissue (sclerosis). The inflammation occurs when the body's own immune cells attack the nervous system.
Multiple sclerosis affects an estimated 300,000 people in the United States and probably more than 1 million people around the world ? including twice as many women as men. Most people experience their first signs or symptoms between ages 20 and 40. MS can cause a variety of symptoms, including is changes in sensation, visual problems, muscle weakness, depression, difficulties with coordination and speech, severe fatigue, cognitive impairment, problems with balance, overheating, and pain. Multiple sclerosis may take several different forms, with new symptoms occurring either in discrete attacks or slowly accruing over time. Between attacks, symptoms may resolve completely, but permanent neurologic problems often persist, especially as the disease advances. MS will cause impaired mobility and disability in more severe cases.
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