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What is isotretinoin?
* Isotretinoin is a form of vitamin A. It decreases the amount of sebum (oil) that is released by the sebaceous (oil) glands, and it increases that rate at which the skin renews itself.
* Isotretinoin is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.
* Isotretinoin may also be used for purposes other than those listed in this medication guide.
What should I discuss with my doctor before taking isotretinoin?
* Before taking isotretinoin, tell your doctor if you have
o a personal or family history of mental problems including depression, suicidal behavior, or psychosis (loss of contact with reality, hearing voices, or seeing things that are not there);
o diabetes;
o asthma;
o heart disease;
o osteoporosis (bone loss) or weak bones;
o anorexia nervosa;
o high cholesterol or triglyceride levels (types of fat) in the blood; or
o liver disease.
* You may not be able to take isotretinoin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
* Do not take isotretinoin if you are pregnant or if you could become pregnant during treatment or for one month after you stop taking isotretinoin. Isotretinoin is in the FDA pregnancy category X. This means that isotretinoin is known to cause severe birth defects in an unborn baby. If you become pregnant, stop using birth control, or miss your menstrual period, immediately stop taking isotretinoin and notify your doctor.
* It is not known whether isotretinoin passes into breast milk. Do not take isotretinoin without first talking to your doctor if you are breast-feeding a baby.
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