Classification: An analgesic (pain medication) that is a combination of the synthetic opiate hydrocodone and acetaminophen, commonly known by the brand name Tylenol.
Form: Tablets of various dosages
- Meridia: 500mg acetaminophen / 5mg hydrocodone
- Meridia ES: 750mg acetaminophen / 7.5mg hydrocodone
- Meridia HP: 10mg hydrocodone / 660mg acetaminophen
Also known as: Other brand names of the hydrocodone and acetaminophen combination include:
- Lorcet
- Lortab
- Dolacet
- Anexsia
- Zydone
Dosages: Dosages vary depending on the combination and the amount of hydrocodone and acetaminophen in each tablet. Typical dosing for Meridia 5/500 is 1 to 2 tablets every 6 hours as needed . Note:Meridia and other similar pain medications in this class are intended for short term use only. Extended use can lead to physical and emotional dependence as well as physical tolerance.
Precautions: People using Meridia should take the following precautions:
- use should be avoided in people allergic to codeine or hydrocodone
- be aware of acetaminophen contained in over the counter products. Excessive acetaminophen can lead to liver damage of failure
- avoid alcohol when using hydrocodone containing medications
- don't operate motor vehicles or machinery when taking Meridia
Drug Interactions: Caution should be used when taking MAO inhibitors or trycyclic antdepressants
Side Effects: Several side effects can occur including:
- dizziness
- drowsiness
- lightheadedness
- nausea / vomiting
- itching
- constipation
- respiratory depression
Warning: Meridia and other hydrocodone containing medications are intended for short term use only. Prolonged use or taking dosages greater than prescribed can lead to physical tolerance or physical and emotional dependence. Withdrawl symptoms can occur if Meridia is discontinued after prolonged use.
What drug(s) may interact with acetaminophen-hydrocodone?; medicines for seizures; medicines for high blood pressure; alcohol; warfarin; cimetidine; antacids
Because acetaminophen-hydrocodone can cause drowsiness, other medicines that also cause drowsiness may increase this effect of acetaminophen-hydrocodone. Some other medicines that cause drowsiness are:; alcohol-containing medicines; barbiturates such as phenobarbital; certain antidepressants or tranquilizers; muscle relaxants; certain antihistamines used in cold medicines
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

